Brandy Hackert joined the Oglesby lab in the summer of 2019. In her previous research, Brandy studied the effect of oxidative damage on DNA during replication in Escherichia coli. Currently, Brandy is characterizing the Pseudomonas aeruginosa protein BrnD, a putative bacterioferritin that is induced by iron in a PrrF-dependent manner. Brandy’s goal is to determine the role that BrnD plays in P. aeruginosa iron homeostasis and oxidative stress.
Nazaretyan SA, Savic N, Sadek M, Hackert BJ, Courcelle J, Courcelle CT (2017). Replication rapidly recovers and continues in the presence of hydroxyurea in Escherichia coli. J Bacteriol. 2017 Dec 20.
Jeiranian HA, Schalow BJ, Courcelle J. (2012) Fate of the Replisome Following Arrest by DNA damage in Escherichia coli. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11421-6
Schalow BJ, Courcelle CT and Courcelle J. (2012) Mfd is required for rapid recovery of transcription following UV-induced DNA damage but not oxidative DNA damage in Escherichia coli. J Bacteriol. 2012 May;194(10):2637-45.
Schalow BJ, Courcelle CT, and Courcelle J. (2011) Escherichia coli Fpg Glycosylase Is Nonredundant and Required for the Rapid Global Repair of Oxidized Purine and Pyrimidine Damage In Vivo. J Mol Biol. Jul 8;410(2):183-93.
Jeiranian HA*, Schalow BJ*, Courcelle J. (2010) Visualization of UV-Induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis. J Vis Exp. Dec 21(46) *contributed equally