Cassie completed her doctoral training in the Biological Sciences Department at the University of Maryland, Baltimore County in the fall of 2017. Using a combination of transcriptomics, microbial genetics and physiology, her dissertation work determined the physiological roles of the glycoside hydrolase family 3 enzymes in the bacterium Cellvibrio japonicus. She is currently studying how the sequestration of metals by the immune system affects the physiology and interactions between Pseudomonas aeruginosa and Staphylococcus aureus.
Publications:
Nelson CE, Huang W, Brewer LK, Nguyen AT, Kane MA, Wilks A, Oglesby-Sherrouse AG. (2018) Proteomic analysis of the Pseudomonas aeruginosairon starvation response reveals PrrF sRNA-dependent iron regulation of twitching motility, amino acid metabolism, and zinc homeostasis proteins. Journal of Bacteriology. 201(12):e00754-18.
Zygiel EM, Nelson CE, Brewer LK, Oglesby-Sherrouse AG, Nolan EM. (2019) The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa. Journal of Biological Chemistry 294 (10):3549-3562. Recommended on F1000 Prime: https://f1000.com/prime/734831237
Nelson CE, Attia MA, Rogowski A, Morland C, Brumer H, Gardner JG. (2017) Comprehensive functional study of the four Glycoside Hydrolase Family 3 members from the soil saprophyte Cellvibrio japonicus reveals unique metabolic roles in plant cell wall saccharificiation. Environmental Microbiology. Accepted Author Manuscript. doi: 10.1111/1462-2910.13959
Nelson CE, Rogowski A, Morland C, Wilhide JA, Gilbert HJ, Gardner JG. (2017) Systems analysis in Cellvibrio japonicus resolves predicted redundancy of b-glucosidases and determines essential physiological functions. Mol Microbiol. 104(2), 294-305. doi: 10.1111/mmi.13625
Nelson CE, Beri NR, & Gardner JG (2016) Custom fabrication of biomass containment devices using 3-D printing enables bacterial growth analyses with complex insoluble substrates. J Microbiol Methods 130:136-143.
Forsberg Z, Nelson CE, Dalhus B, Mekash S, Loose JS, Crouch LI, Rohr AK, Gardner JG, Eijsink VG, Vaaje-Kolstad G.. (2016) Structural and Functional Analysis of a Lytic Polysaccharide Monooxygenase Important for Efficient Utilization of Chitin in Cellvibrio japonicus. The Journal of Biological Chemistry 291(14):7300-12.
Beury DW, Carter, KA, Nelson C, Sinha P, Hanson E, Nyandjo M, Fitzgerald PJ, Majeed A, Wali N, Ostrand-Rosenberg S. (2016) Myeloid-Derived Suppressor Cell Survival and Function Are Regulated by the Transcription Factor Nrf2. Journal of Immunology 196(8):3470-3478.
Nelson CE & Gardner JG (2015) In-Frame Deletions Allow Functional Characterization of Complex Cellulose Degradation Phenotypes in Cellvibrio japonicus. Applied and Environmental Microbiology 81(17):5968-5975.
Zatakia HM, Nelson CE, Syed UJ, & Scharf BE (2014) ExpR coordinates the expression of symbiotically important, bundle-forming Flp pili with quorum sensing in Sinorhizobium meliloti. Applied and Environmental Microbiology 80(8):2429-2439
The Oglesby Lab 