Alexandria’s work on PrrF and PrrH regulation in Pseudomonas aeruginosa was just accepted for publication by Infection and Immunity! This study establishes the role of the prrF-encoded sRNAs in iron homeostasis and virulence, in particular demonstrating that the prrF locus is required for acute murine lung infection. Congratulations to Alexandria, as well as all of our collaborators who contributed to this study!!
Congratulations to Alexandria on her first lead author paper!!
Chourashi R and Oglesby AG. (2024) Iron starvation induces production of the Pseudomonas aeruginosa RsmY and RsmZ sRNAs in static conditions. J Bacteriol e00278-23.
Peet J, Phan A, Oglesby AG, Nolan EM. (2024) Iron sequestration by murine calprotectin induces starvation responses in Pseudomonas aeruginosa. ACS Infectious Diseases. 10(2) 688-700.
Hoang TM, Huang W, Gans J, Weiner J, Nowak E, Barbier M, Wilks A, Kane MA, Oglesby AG. (2023) The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression. mSphere e00392-23.
Nelson CE*, Huang W*, Zygiel EM, Nolan EM, Kane MA, Oglesby AG. (2021) The human innate immune protein calprotectin elicits a multi-metal starvation response in Pseudomonas aeruginosa. Microbiol Spectr 9(2):e0051921.
The Oglesby Lab 