Iron and bacterial pathogenesis at the University of Maryland School of Pharmacy

Howard County high school student celebrates her research internship in the OS Lab

Chourashi R and Oglesby AG. (2024) Iron starvation induces production of the Pseudomonas aeruginosa RsmY and RsmZ sRNAs in static conditions. J Bacteriol e00278-23.

Peet J, Phan A, Oglesby AG, Nolan EM. (2024) Iron sequestration by murine calprotectin induces starvation responses in Pseudomonas aeruginosa. ACS Infectious Diseases. 10(2) 688-700.

Hoang TM, Huang W, Gans J, Weiner J, Nowak E, Barbier M, Wilks A, Kane MA, Oglesby AG. (2023) The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression. mSphere e00392-23.

Nelson CE*, Huang W*, Zygiel EM, Nolan EM, Kane MA, Oglesby AG. (2021) The human innate immune protein calprotectin elicits a multi-metal starvation response in Pseudomonas aeruginosa. Microbiol Spectr 9(2):e0051921.

Our most recent high school intern, Amy Nackeeran, celebrated her accomplishments at a dinner last week with her two lab mentors, Cassie Nelson and Jonathan Gans. Amy’s project was aimed at determining how natural products could be combined with traditional antibiotics to combat P. aeruginosa infections. In true OS Lab fashion, she also studied how varying iron availability affected the efficacy of these drug combinations. Congratulations on a great internship, Amy, and good luck next year in college!

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