Iron and bacterial pathogenesis at the University of Maryland School of Pharmacy

New publication from the OS Lab

Chourashi R and Oglesby AG. (2024) Iron starvation induces production of the Pseudomonas aeruginosa RsmY and RsmZ sRNAs in static conditions. J Bacteriol e00278-23.

Peet J, Phan A, Oglesby AG, Nolan EM. (2024) Iron sequestration by murine calprotectin induces starvation responses in Pseudomonas aeruginosaACS Infectious Diseases. 10(2) 688-700.

Hoang TM, Huang W, Gans J, Weiner J, Nowak E, Barbier M, Wilks A, Kane MA, Oglesby AG. (2023) The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression. mSphere e00392-23.

Nelson CE*, Huang W*, Zygiel EM, Nolan EM, Kane MA, Oglesby AG. (2021) The human innate immune protein calprotectin elicits a multi-metal starvation response in Pseudomonas aeruginosa. Microbiol Spectr 9(2):e0051921.

Check out our lab’s newest publication, out this month in Journal of Bacteriology! This work was led by former OS graduate student Dr. Louise Djapgne. Dr. Djapgne detailed the biochemical and genetic basis by which the PrrF sRNAs modulate the production of the PQS quorum signaling molecule. This study was performed as a part of our ongoing collaboration with Dr. Sarah Woodson at Johns Hopkins University, and included work from OS Lab members Luke Brewer and Jonathan Gans. Congratulations all on a great publication!