Iron and bacterial pathogenesis at the University of Maryland School of Pharmacy

Welcome new OS Lab members!

Chourashi R and Oglesby AG. (2024) Iron starvation induces production of the Pseudomonas aeruginosa RsmY and RsmZ sRNAs in static conditions. J Bacteriol e00278-23.

Peet J, Phan A, Oglesby AG, Nolan EM. (2024) Iron sequestration by murine calprotectin induces starvation responses in Pseudomonas aeruginosa. ACS Infectious Diseases. 10(2) 688-700.

Hoang TM, Huang W, Gans J, Weiner J, Nowak E, Barbier M, Wilks A, Kane MA, Oglesby AG. (2023) The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression. mSphere e00392-23.

Nelson CE*, Huang W*, Zygiel EM, Nolan EM, Kane MA, Oglesby AG. (2021) The human innate immune protein calprotectin elicits a multi-metal starvation response in Pseudomonas aeruginosa. Microbiol Spectr 9(2):e0051921.

The OS Lab has grown quite a bit this past year, welcoming a new postdoctoral fellow, graduate student, and PharmD student.

8k0%cKemRnCf742jLRQpmQ_thumb_7726Dr. Tra-My Hoang joined the OS lab this fall after completing her Ph.D. studies in the lab of Dr. Paul Fey at the University of Nebraska. Tramy is studying the impact of the heme-responsive PrrH sRNA on P. aeruginosa growth and gene expression.

kmX%scBHSh6n+4AzWYUKtA_thumb_7725Ashley Lykins conducted rotation studies in the OS lab in the fall of 2017, and officially joined the OS Lab this fall. Ashley is studying the mechanism by which the PrrF sRNAs regulate of a putative bacterioferritin produced by P. aeruginosa.

IMG-0038Xinyi (Xena) Huang is a second-year PharmD student who began a research internship in the OS Lab this past summer. She is studying the impact of iron and antimicrobials on co-cultured biofilms of P. aeruginosa and S. aureus.

Welcome to all the new OS Lab members!